Monthly Archives: July 2023

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Histamine, migraine and PMS

Category : Uncategorized

So what about histamine and MIGRAINE? Specifically migraine that many women experience with PMS or before out menses?

Histamine symptoms are actually more common in women because of our hormones,  and often track with the menstrual cycle, occurring when estrogen is high at ovulation and then again just before the period AKA PMS.

  • Estrogen stimulates mast cells to release histamine and down-regulates the DAO enzyme that clears histamine. While, histamine stimulates the ovaries to make more estrogen. The net result can be a vicious cycle of estrogen → histamine → estrogen → histamine.
  • Progesterone stabilizes mast cells, up-regulates DAO, and can therefore reduce histamine… but most women have issues with low progesterone due to chronic stress. So of course are not metabolizing and detoxifying histamine efficiently.
  • It is proposed that symptoms of estrogen dominance are actually symptoms of high estrogen.

Several symptoms on the symptoms list here are typical symptoms of PMS which makes sense because histamine rises and falls with estrogen. Histamine is highest just before ovulation and then again during the days before the period. Histamine can also cause period pain because of its inflammatory effect.

Read the full article here.

 


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Tricks and tips for a better nights sleep!

Category : Uncategorized

Tricks and Tips for a Better Night’s Sleep;

If you have been following me (at all) and have seen the studies in here (in my Facebook group) on how poor sleep slows metabolism thyroid, and more… then you KNOW how important sleep and sleep optimization is.
The basics are pretty simple and can be all some people need:
Shut down your computer, cell phone, and TV at “least” an hour before you hit the sack. All electronics off, ideally 60-90 minutes before your head hits the pillow. We want as little stimulation as possible in the evenings.
• Save your bedroom for sleep and sex. Think relaxation and release, rather than work or entertainment. If you are a highly strung person – running on adrenaline and cortisol all day – then reading before bed with a candle, orange or red light for lighting may be just the ticket for you to shut off your brain.
• Create an evening routine and bedtime ritual. And DO IT! It’s not the time to tackle big issues or do the laundry. Instead, take a warm bath, meditate, or read, or do something relaxing. Think – “I need to push my stress hormones down”.
• Stick to a schedule, waking up and retiring at the same times every day, even on weekends. Work with your circadian rhythms, instead of against it. Research shows us that having consistent sleep wake times not only encourages better sleep but also good hormonal patterns.
• Watch what and when you eat. Avoid eating heavy meals and alcohol close to bedtime, which may also cause gut and blood sugar issues, and make it hard to fall asleep and get into DEEP sleep. And steer clear of soda, tea, coffee, and dark chocolate after 1/2 p.m. Caffeine can stay in your system for 8-12 hours. If you have sleep issues then I advise no caffeine after noon.
• Turn out the lights. Darkness cues your body to release more of the natural sleep hormone “melatonin”, while light suppresses it. INCLUDING the little red light on the TV or clock. Research shows us that for every 30 minutes of blue light exposure suppresses melatonin for up to 90 minutes. So if you are watching tv before bed, then you are suppressing your melatonin and ability to get into deep sleep. 
 
Having a quiet cool room is essential for good sleep. The body like to be cool when sleeping to get into deep and REM sleep, and if there is any background noise (white noise may be the exception), it can stop you getting into deep sleep – even when you don’t think its a big deal or effects you. Essential oils may help too – Lavender and Vetiver are good options. 
Check out my podcast on “Deep sleep” to understand more on how to help your sleep; 

But sometimes people need a little more help. This is where we look at aids like;
  • Calming teas such as Reishi, Tulsi, Valerian, Passionflower, Chamomile and Skullcap.
  • Magnesium which is a relaxant and helps relieve tension throughout the muscles and nervous system. Magnesium citrate can act as a mild sedative that helps the body to fall asleep. It also increases deep sleep and decreases nighttime cortisol. I like to start at 300-400 mg before bed.
  • GABA which is an anxiety blocker. Most people who have insomnia or wake during the night are suffering from anxiety. The adrenaline and cortisol dump during the night wakes them and then they struggle to fall back asleep. GABA is beneficial for many people dealing with this and Adrenaline Dominance.
  • Collagen in the evening can be very beneficial due to its glycine and ability to push you into deep sleep. Glycine also helps with blood sugars, inflammation and dropping the body’s core temperature – all essential for optimizing recovery!
  • Ashwagandha taken from 6pm onwards can help shut down cortisol and improve melatonin and sleep quality. This is generally in supplement form.
Then there are some people who need EVEN MORE help! In this case we might consider one or a couple of these;
  • Topical progesterone 5%. There is research and a lot of supporting work by Dr Michael E Platt on the effectiveness of topical progesterone from pushing down adrenaline, cortisol and inflammation, and thus supporting good sleep.
  • CBDa can be very helpful at relaxing the body and supporting sleep quality.
  • Melatonin in doses from 3-10mg can be helpful for some people, but if you find yourself groggy the next day or feeling “off” you may need a lower dose, split doses, or your body doesn’t actually need melatonin – its making enough of its own.
  • Tryptophan is a precursor to Serotonin and Melatonin. You can boost Tryptophan in the evening by consuming; turkey, chicken, eggs, pumpkin seeds, sesame seeds, avocado and white fish. Calcium and vitamin B6 help with absorption. You can also get a supplement of L-Tryptophan taken twice daily, once with carbs, and the second before bed. You can help convert Tryptophan to 5-HTP by pairing it with vitamin C and folate. 
  • Taurine has been shown to push down stress and anxiety, and increases the body’s natural GABA production. Doses range from 500-1500mg before bed.
  • Theanine or L-theanine increases alpha waves (found in REM sleep).
  • Vitamin B6 before sleep can help with REM sleep and remembering dreams. We would be looking at 240mg here.
  • Zinc and vitamin C may support sleep. Zinc boosts testosterone and vitamin C can help with progesterone. Sufficient levels of both are calming and help with sleep quality.

To be used as a last resort…

One could stack 5 HTP with melatonin and hour before going to bed. The effect can be improved with B6 and Zinc. ZMA or zinc+magnesium+B6 can also be effective.

Its important to also note;

Getting direct sunlight early in the day (or blue light spectrum), especially after waking is an important player in the circadian rhythms, hormones and sleep. Blood sugars can greatly influence sleep, you should work on balancing them. Some studies also show that grounding can help with sleep and insomnia. Reference. 

Exercise has also been shown to greatly improve sleep quality, deep and Rem. Reference. 

Avoid substance that can effect sleep negatively like;

  • Caffeine
  • Theobromine and theophylline (cacao and kola nut)
  • Alcohol
  • Excess sugar
  • Tyramine containing foods (bacon, cheese, eggplant, potato, tomato, spinach, sausage).

I hope you found this helpful and please reach out if you have any questions! And will maybe try these before resorting to medications. Good luck on your sleep quest! xo

 

 

 


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Parasites.

Category : Health

I recently got asked about parasites, by several of my followers actually, so I went ahead and recorded the below podcast on “How to do a parasite cleanse at home”. But while doing my research I came across some important information and interesting facts around parasites. I hope you find this interesting and helpful!

Parasites are prevalent in our enviroment and many of us have them inside us. It really is not uncommon to get a diagnosis of parasites. Especially if you travel frequently, spend a lot of time outdoors, or even have pets (and dare I say kids).

A parasite is an organism that infects the body of another living being and live off their hosts to survive. In other words it gets its food from or at the expense of its host. The parasite uses the resources of the person it’s living inside of, such as the blood (like a vampire), or the very food that that person eats, in order to survive. Parasites can be very small or meters long. Gross!

Some parasites create no symptoms at all in their hosts, while others can cause lots or symptoms and severe illness. Parasitic infections occur when parasites grow, reproduce, or invade organ systems (including the brain), that make their hosts sick. Symptoms include atopic dermatitis, rashes, allergies, excess mucus, diarrhea, nausea,  grinding of the teeth, sleep issues, inflammation/ aches and pains in the joints, and in worse cases fever, flue like symptoms, and swollen lymph nodes.

Some common human parasitic infections include the following: toxoplasmosis, giardiasis, cryptosporidiosis and trichomoniasis (which is actually an STI).

You can get tested for parasites through a blood test (looking for higher eosinophils) or stool test. Your doctor may have to test your stool more than once before you test positive for parasites… at least a 3 day stool test/collection is recommended and has been shown to give a 90% accurate result. Some people might even see worms move in the bottom of the toilet (gross!).

𝘿𝙞𝙙 𝙮𝙤𝙪 𝙠𝙣𝙤𝙬…
#parasite eggs hatch and spit out ammonia around the full moon. 🌕
So people with parasites can experience a lot more, or exasperated symptoms like atopic dermatitis, allergies, sleep issues, irritability and erratic behavior, and gut problems around the full moon. Children with parasites can be more challenging around this time too.
Crazy right?! 🤯

 

Some other interesting facts about parasites;
  • Worm therapy or treating people with worms, specifically helminths, is a thing! Treating people with parasitic worms may help with reducing inflammation and increasing lifespan (anti aging) by increasing T helper 2 cells, and reducing T helper 1 cells. Check it out here.
  • Parasites release a biproduct called ammonia which has lots of negative effects including mental health issues and changes in personality. Read here. 
  • Parasites can not only upset the gut and contribute to IBD issues, the can also disrupt the microbiome by encouraging the growth of bad bacteria like klebsiella which increases inflammation and has been connected to ankylosing spondylitis, AND effects your bodies synthesis of vitamin B12. Tape worm also can cause B12 deficiencies.
  • Parasites can cause micronutrient deficiencies because they are basically stealing our food.
  • Hookworms which feed off our blood (gross again!), can contribute to anemia and protein deficiencies. Reference.
  • Worms can directly effect our mental and adrenal health by directly reducing serotonin, dopamine, adrenaline and noradrenaline. This effects motivation and energy levels too. (ADHD , schizophrenia and depression included.)
  • Parasites can contribute to weight gain due the the inflammatory and stress response, nutritional deficiencies, and the lack of motivation to make good food choices or go exercise because of their impact on mental health above.
  • Worms, in one study, were shown to help with viral infections by reducing the inflammatory storm. Reference.
  • Worms, specifically tape worm can cross into the brain and lay eggs. This has been connected to seizures and Alzheimer’s. You can Google a picture of the brain that shows tunnels in the tissue and throughout the brain, its crazy!
  • Simple herbs like garlic, turmeric, and licorice can act as an anti parasitic. Along with binders like diatomaceous earth (food grade) and activated charcoal.
  • PUMPKIN SEEDS have long been used as a substance that helps expel intestinal parasites. Pumpkin seeds contain high levels of compounds known as cucurbitacin’s, which paralyze the worms. This prevents them from holding on to the intestinal walls, as they usually do during a bowel movement – thus allowing them to be expelled with your poop.

 

I hope you found this interesting and enjoy the podcast episode!